REACTIONS TO INTRAVENOUS AGENTS (ALTHESIN AND PANCURONIUM)
نویسندگان
چکیده
منابع مشابه
Althesin--a new intravenous anaesthetic.
IN 1941, Selye 1 noted the anaesthetic effect of some steroids in animals. Fourteen years later, Murphy e t al . 2 reported on the use of a steroid hydroxydione to produce clinical anaesthesia. This agent, when given intravenously, has a gradual onset of action and produces prolonged sleep with little disturbance to the cardiovascular and respiratory systems and no hangover effect. Unfortunatel...
متن کاملIdentification and quantitation of hypersensitivity reactions to intravenous anaesthetic agents.
It is not possible to distinguish between direct pharmacological effects and immune-mediated hypersensitivity reactions by clinical observation alone and errors may occur in the absence of laboratory tests. A convenient and simple test is the measurement of plasma complement C3 consumption and conversion in sequential blood samples taken at intervals over the 24 h following an adverse response.
متن کاملPotentiation of pancuronium and vecuronium neuromuscular blockade by intravenous salbutamol.
Three doses of salbutamol 125 micrograms iv were given, over 3.5 hr, to a 28-yr-old healthy, previously non-asthmatic man during thiopentone-O2/N2O-isoflurane anaesthesia for treatment and prophylaxis of bronchospasm. Force of contraction of the adductor pollicis was measured before and after the last two injections. Initially, the patient was given pancuronium, 5 mg. Salbutamol, 125 micrograms...
متن کاملAlthesin: a group trial as an intravenous anaesthetic.
THE initial clinical trials of a drug usually only provide information pertaining to its use in strictly defined circumstances, often with a small number of highly trained observers. For this reason, when the circumstances permit, this should be followed by a 'group trial' prior to its general release. The purpose of this is to provide information, often not obtained from the controlled clinica...
متن کاملClinical studies of induction agents. XL. Althesin with various premedicants.
Althesin, the new steroid anaesthetic, has been given to patients having minor gynaecological operations after six different premedicant combinations. Atropine, which had been studied previously, was a satisfactory premedicant in terms of both induction and recovery and diazepam 10 nag was not very different. Hyoscine, given before Althesin 50 /"I/kg, increased the incidence of involuntary musc...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1974
ISSN: 0007-0912
DOI: 10.1093/bja/46.3.244